VAXESS

January 7, 2020

Implantable silk composite microneedles for programmable vaccine release kinetics and enhanced immunogenicity in transcutaneous immunization

DeMuth PC et al.,

Study details the fabrication of silk-based dissolving microneedles for sustained release of a model antigen, ovalbumin, and demonstrates in mice the immunological benefits of sustained vaccine release over a time course that mimics natural infection.

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